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The suggestions offeredmay include replication with larger samples, use of more homogeneous or heterogeneousgroups of people depending on the nature of the study, refinements in design or measure-ment techniques, or improvements in materials or instrumentation.

It forms filaments thatrun in the groove between the F-actin molecules in thethin filament.

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Bias underminesthe aforementioned validity of a study and contingent onmanifestation may compromise the earlier described internaland/or external study validities.

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